Dynamic gene regulatory networks of human myeloid differentiation [RNA-seq]

We utilize gene expression and open chromatin footprinting data to build a gene regulatory network of key transcription factors that capture the cell and time-specific regulatory programs specified during human myeloid differentiation. Overall design: RNA-seq profiling of undifferentiated HL-60, differentiating macrophage, neutrophil, monocyte, and monocyte-derived macrophage cells.

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Ramirez RN, El-Ali NC, Mager MA, Wyman D, Conesa A, Mortazavi A