Transcriptome of new DGCR8_KO mouse embryonic stem cells generated by paired CRISPR/Cas9 approach

SRP071252

Mus musculus

2 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular pathways. The goals of this study was to obtain the trasncriptome of DGCR8_KO mESCs to compare it with the transcriptome of WT mESCs (deposit separately). Overall design: mRNA profiles of DGCR8_KO mouse embryonic stem cells were generated by deep sequencing, in duplicate, using Illumina HiSeq2000.

PubMed ID

28100686

Publication Title

Noncanonical function of DGCR8 controls mESC exit from pluripotency.

Total Samples

Submitter’s Institution

No associated institution

Authors

Cirera-Salinas D, Yu J, Bodak M, Ngondo RP, Herbert KM, Ciaudo C

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE78974

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