Pdx1-Oc1 cooperatively drive the induction of the endocrine pancreatic program

SRP070076

Mus musculus

16 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

We report the impact of heterozygous loss of either Pdx1 or Oc1 on the developing pancreas at e15.5 Overall design: mRNA of mouse pancreata at embryonic day 15.5 from control, Pdx1Lac/+, Oc1+/- and double heterozygous (Pdx1LacZ/+;Oc1+/-) embryos

PubMed ID

27292642

Publication Title

Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.

Total Samples

Submitter’s Institution

No associated institution

Authors

Henley KD, Stanescu DE, Kropp PA, Wright CVE, Won KJ, Stoffers DA, Gannon M

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE77896

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