RNA Sequencing Analysis of Wild Type and Ezh2 knock out CD8 T cell Transcriptomes

SRP068326

Mus musculus

12 Downloadable Samples

Illumina Genome Analyzer

Submitter Supplied Information

Description

Our data represents the first analysis of histone methyltransferase Ezh2 regulated transcriptomes in mouse CD8 T cells. Overall design: NaÃ¯ve and in vitro TCR stimulated CD8 T cell mRNA profiles of Pmel-1 wild type (WT) and Ezh2-/- mice were generated by deep sequencing, in triplicate, using Illumina.

PubMed ID

29242551

Publication Title

Ezh2 phosphorylation state determines its capacity to maintain CD8<sup>+</sup> T memory precursors for antitumor immunity.

Total Samples

Submitter’s Institution

No associated institution

Authors

He S, Liu Y, Meng L, Sun H, Wang Y, Ji Y, Purushe J, Chen P, Li C, Madzo J, Issa JP, Soboloff J, Reshef R, Moore B, Gattinoni L, Zhang Y

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE76755

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