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Accession IconSRP066716

Downregulation of neuropilin-1 on macrophages modulates antibody-mediated tumoricidal activity

Organism Icon Homo sapiens
Sample Icon 4 Downloadable Samples
Technology Badge IconIon Torrent Proton

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Description
We reported that NRP-1 expression on CD4+ T cells was probably induced by NRP-1 transfer from macrophages to T cells. In HER2+ BC, NRP-1 expressing TIIs correlated with better clinical outcomes. Overall design: Examination of monocytes and monocyte derived macrophages.
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4
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