Differential Gene Expression in Mouse Bone Marrow in Response to Dibenzo[def,p]chrysene by RNA-Seq

The immunotoxicity of Dibenzo[def,p]chrysene (DBC) was investigated following acute exposure of adult Mutaâ„¢Mouse males by oral gavage. Mice were exposed to 0, 2, 6.3 and 20.0 mg DBC /kg-bw per day, for three days. Global gene expression changes were measured in bone marrow 24 hours after the last exposure.

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Chepelev NL, Long AS, Williams A, Kuo B, Gagné R, Kennedy DA, Phillips DH, Arlt VM, White PA, Yauk CL