Using single-cell RNA-Seq for unbiased analysis of developmental hierarchies (Bulk RNA-Seq)

Single cell RNA seq and bioinformatic analysis is used to characterize myeloid differentiation to uncover novel transcriptional networks and key drivers of hematopoietic development Overall design: Single-cell RNA Seq of 4 different hematopoietic populations, integrated with ChIP Seq involving 4 different markers

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Olsson A, Venkatasubramanian M, Chaudhri VK, Aronow BJ, Salomonis N, Singh H, Grimes HL