Transcriptional profile of C. elegans following over-expression of elt-2 [L4 stage & Day 13]

SRP058747

Caenorhabditis elegans

20 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

We used RNA-seq to discover that gene expression changes during aging are attenuated in elt-2 overexpressors relative to controls Overall design: Whole-worm mRNA was sequenced from worms over-expressing elt-2 and control worms. Five biological replicates were collected for each condition.

PubMed ID

27070429

Publication Title

Deactivation of the GATA Transcription Factor ELT-2 Is a Major Driver of Normal Aging in C. elegans.

Total Samples

Submitter’s Institution

No associated institution

Authors

Mann FG, Van Nostrand EL, Friedland AE, Liu X, Kim SK

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE69263

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