Retinoids induce rapid dynamic changes in the non-coding RNAs and epigenetic profiles of murine Hox clusters.

SRP056899

Mus musculus

16 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

Physiologically relevant concentrations of retinoic acid are added to Mouse ES cells and a time course (0-72 hours) is examined with expression tiling arrays and RNA-seq to characterize the early dynamics of expression of coding and non-coding RNAs in and around the Hox clusters. Overall design: Gene expression is examined at various timepoints (0-72 hrs) after retinoic acid induced neuronal differentiation

PubMed ID

28584089

Publication Title

Dynamic regulation of Nanog and stem cell-signaling pathways by Hoxa1 during early neuro-ectodermal differentiation of ES cells.

Total Samples

Submitter’s Institution

No associated institution

Authors

De Kumar B, Parker HJ, Parrish ME, Lange JJ, Slaughter BD, Unruh JR, Paulson A, Krumlauf R

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE67610

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