RNA-seq in squamous cell carcinoma stem cells in the presence or absence of TGF-beta signaling

We performed RNA-seq on purified squamous cell carcinoma stem cells (SCC-SCs) from primary mouse skin tumors transduced with TGF-beta reporter. Overall design: SCC-SCs were purified based on cell surface marker expression integrin alpha6 and CD44, after lineage negative selection, and separated by fluorescent TGF-beta reporter expression.

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Oshimori N, Oristian D, Fuchs E