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Accession IconSRP051995

RNA-Seq of osteoclasts derived from WT and Chmp5 CKO mice

Organism Icon Mus musculus
Sample Icon 6 Downloadable Samples
Technology Badge IconIllumina HiSeq 2500

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Description
The activities of osteoclasts to break down bone and osteoblasts to build bone are coupled, and this coupling is a key determinant of physiologic bone remodeling. In this study, we discovered that charged multivesicular body protein 5 (CHMP5) is a key regulator of bone turnover and osteoclast/osteoblast coupling.
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6
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