Top2a identifies and provides epigenetic rationale for novel combination therapeutic strategies for aggressive prostate cancer

We perform RNA-seq on matched orthotopic murine primary and metastatic prostate cancer samples to identify differential gene expressions Overall design: RNA-seq was performed on orthotopic murine primary and metastatic tumor samples using Illumina Hi-Seq 2000 platform

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Kirk JS, Schaarschuch K, Dalimov Z, Lasorsa E, Ku S, Ramakrishnan S, Hu Q, Azabdaftari G, Wang J, Pili R, Ellis L