Next Generation Sequencing Comparison of C57BL/6J and BC027072 -/- Eye Transcriptomes

SRP050483

Mus musculus

6 Downloadable Samples

Illumina HiSeq 2500

Submitter Supplied Information

Description

We report the single base pair analysis of the ocular transcriptome from wild type and BC027072 knockout animals. Comparison was analyzed to understand gene expression changes in a mouse model for early onset retinal degeneration which phenocopies a human form of autosomal recessive retinitis pigmentosa Overall design: Eye mRNA profiles were generated from 3 week-old C57BL/6J and BC027072 -/- in triplicate and sequenced using the Illumina HiSeq 2500

PubMed ID

25616964

Publication Title

Animals deficient in C2Orf71, an autosomal recessive retinitis pigmentosa-associated locus, develop severe early-onset retinal degeneration.

Total Samples

Submitter’s Institution

No associated institution

Authors

Kevany BM, Zhang N, Jastrzebska B, Palczewski K

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE63810

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