Impact of Tcf1 and Lef1 deficiency on HSCs

SRP045665

Mus musculus

4 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

Comparison of transcriptome between control and Tcf1/Lef1-deficient hematopoietic stem cells (HSCs). Overall design: Flt3-negative, lineage-negative, Sca1+ and cKit+ cells (Flt3-LSKs) were sorted from bone marrow cells from control mice or those are deficient for Tcf1 and Lef1 transcription factors. Both genes were conditionally deleted using Vav-Cre

PubMed ID

28844837

Publication Title

Prostaglandin E1 and Its Analog Misoprostol Inhibit Human CML Stem Cell Self-Renewal via EP4 Receptor Activation and Repression of AP-1.

Total Samples

Submitter’s Institution

No associated institution

Authors

Li F, He B, Ma X, Yu S, Bhave RR, Lentz SR, Tan K, Guzman ML, Zhao C, Xue HH

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE60587

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