Genes regulated by the winged helix transcription factor Rfx6 in adult beta cell in the mouse

SRP044675

Mus musculus

6 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

The goal of this study was to identify genes which are differentiatlly expresesd upon induced inactivation of Rfx6 in beta cell in adult mice Overall design: Rfx6fl/fl; Ins1-CreERT2 (mut) and Rfx6fl/fl (ctrl) 8 weeks old mice were injected subcutaneously with tamoxifen daily during 3 days. Pancreatic islets were isolated 5 days after the first injection and RNA purified.

PubMed ID

25497096

Publication Title

Rfx6 maintains the functional identity of adult pancreatic β cells.

Total Samples

Submitter’s Institution

No associated institution

Authors

Piccand J, Strasser P, Hodson DJ, Meunier A, Ye T, Keime C, Birling MC, Rutter GA, Gradwohl G

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE59622

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