Molecular Effects of Doxycycline Treatment on Pterygium from Caucasian Patients as Revealed by Massive Transcriptome Sequencing

SRP043166

Homo sapiens

12 Downloadable Samples

Illumina Genome Analyzer IIx

Submitter Supplied Information

Description

Genes were identified which modified their expression in a dose-dependent manner upon exposure to doxycycline. The more represented cellular pathways included all mitochondrial genes, the endoplasmic reticulum stress response, integrins and extracellular matrix components, and growth factors. Overall design: Examination of 4 different doses of doxycycline in three human pterygium samples.

PubMed ID

25358733

Publication Title

Transcriptomic profiling explains racial disparities in pterygium patients treated with doxycycline.

Total Samples

Submitter’s Institution

No associated institution

Authors

Larrayoz IM, Rúa Ó, Velilla S, Martínez A

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE58441

No rows found