Genome wide analysis of gene expression in LPS stimulated splenic B cell.

Analysis of class switch recombination, maturation or differenciation of B cells at gene expression levels. The hypothesis tested in the present study was that TLR signaling in B cells plays an pivotal role for class switch, maturation and differenciation. Overall design: Total RNA obtained from cultured splenic B cells. Gene expression compared between control and cKO B cells.

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Hanihara-Tatsuzawa F, Miura H, Kobayashi S, Isagawa T, Okuma A, Manabe I, MaruYama T