Treatment of multiple myeloma cells with EZH2 small molecule inhibitor

SRP041819

Homo sapiens

8 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

We investigated differential gene expression in response to treatment of multiple myeloma cells with EZH2 inhibitor Overall design: RNA-seq in two cell lines

PubMed ID

25188243

Publication Title

Histone methyltransferase MMSET/NSD2 alters EZH2 binding and reprograms the myeloma epigenome through global and focal changes in H3K36 and H3K27 methylation.

Total Samples

Submitter’s Institution

No associated institution

Authors

Popovic R, Martinez-Garcia E, Giannopoulou EG, Zhang Q, Zhang Q, Ezponda T, Shah MY, Zheng Y, Will CM, Small EC, Hua Y, Bulic M, Jiang Y, Carrara M, Calogero RA, Kath WL, Kelleher NL, Wang JP, Elemento O, Licht JD

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE57478

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