Gene expression analysis of human primary lung fibroblast cell line IMR-90 infected by adenovirus type 2

In the present study adenovirus type 2 RNA splicing events were quantitatively mapped by using deep cDNA sequencing. The majority of the previously identified splice sites could be confirmed. The lack of complete consistency between the present and previous results appears to be that some sites have been incorrectly mapped in previous studies, such as the splice sites for pVII, pVIII and E3-11.6K. everal previously predicted splice sites such as that for E3-14.5K and E4ORF3/4 were not detected.

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Zhao H, Chen M, Pettersson U