Genome-wide expression profiling of B Lymphocytes reveals IL4R increase in allergic asthma

In this study we present the first genome-wide expression profiling of peripheral B cells by massive parallel RNA sequencing in patients with allergic asthma validating the discovery potential of this approach in allergy. Overall design: RNA-seq was used to asses expression differences in B CD19 Lymphocytes from house dust mite allergic patients and healthy controls.

6

Pascual M, Roa S, García-Sánchez A, Sanz C, Hernandez-Hernandez L, Greally JM, Lorente F, Dávila I, Isidoro-García M