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Accession IconSRP029274

Mining gene expression data for low doses of radiation and pollutants (dioxin, toluene, formaldehyde)

Organism Icon Drosophila melanogaster
Sample Icon 38 Downloadable Samples
Technology Badge IconIllumina HiSeq 2000

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Description
Expression profiles of Drosophila melanogaster in response to ionizing radiation, formaldehyde, toluene, and 2,3,7,8-tetrachlorodibenzo-p-dioxin. Overall design: RNA-seq analysis on 25,415 transcripts to measure the change in gene expression in males and females separately. An analysis of the genes unique to each treatment yielded a list of genes as a gene expression signature. In the case of radiation exposure, both sexes exhibited a reproducible increase in their expression of the transcription factors sugarbabe and tramtrack.
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40
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