Feeding with miR-184 affects the mRNA expression profile of queen larvae

By comparing mRNA profiles of the two groups of bee larvae (treated by miR-184 and water), we found that there were 279 mRNAs which were differently expressed between treated and control larvae (ratio>2 and p<0.01), of which 200 mRNAs were down-regulated in treated larvae, and 79 mRNAs were down-regulated in controls. Overall design: To further study the biological function and potential pathways of microRNAs with RNAi phenotypes, we measured mRNA profiles of bee larvae fed with miR-184 (treated) and water (control).

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Guo X, Su S, Skogerboe G, Dai S, Li W, Li Z, Liu F, Ni R, Guo Y, Chen S, Zhang S, Chen R