Influence of p38 MAPK (PMK-1) on the heat stress response of C. elegans

SRP015918

Caenorhabditis elegans

2 Downloadable Samples

Illumina HiSeq 2000

Submitter Supplied Information

Description

PMK-1 is involved in the heat stress response of C. elegans, translocates to the nucleus upon heat exposure and influences the expression of chaperone genes, proteasomal subunits and protein-biosynthesis related genes. Overall design: Differential Gene expression of WT and pmk-1 deletion mutant (KU25) after 5 hours at 35Â°C

PubMed ID

23117578

Publication Title

The p38 MAPK PMK-1 shows heat-induced nuclear translocation, supports chaperone expression, and affects the heat tolerance of Caenorhabditis elegans.

Total Samples

Submitter’s Institution

No associated institution

Authors

Mertenskötter A, Keshet A, Gerke P, Paul RJ

Source Repository

Sequence Read Archive (SRA)

Alternate Accession IDs

GSE41205

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