Ribosome profiling of wild-type and loc1- cells in S. cerevisiae

We performed ribosome profiling of wild-type and loc1- cells. We found that approximately 1500 genes exhibit increased translational efficiencies in the absence of Loc1, indicating that Loc1 is required for their translational repression. Overall design: Examination of translational efficiencies by comparing ribosome footprints and mRNA abundances in two different cell lines.

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