Quantitative and qualitative RNA-seq based evaluation of Epstein-Barr virus transcription in type I latency Burkitt's lymphoma cells

RNASeq was used to evaluate the Epstein-Barr virus transcriptome. A pipeline was developed for the analysis of EBV specific transcripts and applied to EBV positive Burkitt's lymphoma cells exhibiting type I latency. PolyA fractions of whole cell RNA was sequenced using 74b single-end reads on an Illumina GA2x machine.

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Lin Z, Xu G, Deng N, Taylor C, Zhu D, Flemington EK