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Accession IconSRP002632

Time series of standard and delayed bone healing in Ovis Aries

Organism Icon Ovis aries
Sample Icon 8 Downloadable Samples
Technology Badge IconIllumina Genome Analyzer II

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Description
Fracture healing is a highly complex regenerative process. The sheep is an important large-animal model for studying delayed fracture healing. Here we used next-generation sequencing (Illimuna GA IIx) for gene expression analysis (RNAseq) in two conditional groups - standard and delayed healing. In both groups sequential biopsies 7, 11, 14 and 21 days after surgery were collected from callus tissue and annalized. For all timepoints and conditions the samples were pooled (n=6), except for day 21 standard (n=5).
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8
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