Gene expression in non-adherent MDA-MB-468 subpopulation

Plasticity between adhesive and less-adhesive states is important for mammalian cell behaviour. To investigate adhesion plasticity, we have selected a stable isogenic subpopulation of MDA-MB-468 breast carcinoma cells which grows in suspension. These suspension cells are unable to re-adhere to various matrices or to contract three-dimensional collagen lattices.

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Veß A, Blache U, Leitner L, Kurz ARM, Ehrenpfordt A, Sixt M, Posern G