Gene Microarray analysis of Th17 cells

GSE9316

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

Th17 cells are enriched by sorting FR4-CD4+ T cells from SKG mice. A large number of Th17 cells also develop spontaneously when CD4+ T cells from IFN-g-deficient (IFN-g-/-) BALB/c mice are transferred to T cell-deficient RAG2-deficient (RAG2-/-) mice and subjected to homeostatic proliferation, whereas they fail to develop in similar transfer of IL-6-deficient (IL-6-/-) CD4+ T cells to IL-6-/- RAG2-/- mice.

PubMed ID

18025126

Publication Title

Preferential recruitment of CCR6-expressing Th17 cells to inflamed joints via CCL20 in rheumatoid arthritis and its animal model.

Total Samples

Submitter’s Institution

Institute for Frontier Medical Sciences Kyoto University

Authors

Hirota K, Yoshitomi H, Hashimoto M, Maeda S, Teradaira S, Sugimoto N, Yamaguchi T, Nomura T, Ito H, Nakamura T, Sakaguchi N, Sakaguchi S

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-9316

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