Expression data from triple negative breast cancer cells

GSE90145

Homo sapiens

18 Downloadable Samples

Affymetrix Human Transcriptome Array 2.0 (hta20)

Submitter Supplied Information

Description

Treatment of triple-negative breast cancer has been challenging and paclitaxel resistance is one of the major obstacles to the better prognosis. Misregulation of alternative splicing (AS) may contribute to tumor progression and chemotherapy resistance. Human AS factor TRA2 has two separate gene paralogs encoding TRA2A and TRA2B proteins. TRA2B is associated with cancer cell survival and therapeutic sensitivity.

PubMed ID

28416606

Publication Title

TRA2A Promoted Paclitaxel Resistance and Tumor Progression in Triple-Negative Breast Cancers via Regulating Alternative Splicing.

Total Samples

Submitter’s Institution

Tianjin Medical University

Authors

Liu T, Sun H, Zhu D, Dong X, Liu F, Liang X, Chen C, Shao B, Wang M, Wang Y, Sun B

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-90145

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