Master Regulators of oncogenic KRAS response in Pancreatic Cancer

GSE89846

Mus musculus

24 Downloadable Samples

Illumina MouseWG-6 v2.0 R2 expression beadchip

Submitter Supplied Information

Description

We derived a transcriptional signature of oncogenic KRAS by using the KF508 murine pancreatic ductal cell line with an inducible Lox-Stop-Lox (LSL) cassette in front of the KRASG12D oncogene to regulate transcription. This dataset allowed us to study the differential expression profile after oncogenic KRAS induction in mouse.

PubMed ID

28141826

Publication Title

Master Regulators of Oncogenic KRAS Response in Pancreatic Cancer: An Integrative Network Biology Analysis.

Total Samples

Submitter’s Institution

University of Cambridge

Authors

Sivakumar S, de Santiago I, Chlon L, Markowetz F

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-89846

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