Transcriptome of normal mammary glands of Sprague-Dawley rats at six stages of development: pre-pubertal, peri-pubertal, pubertal, lactation, adult parous and age-matched nulliparous

There is a lack of systematic investigations of large-scale transcriptome patterns associated with normal breast development. Herein, we profiled whole-transcriptome (by microarrays) of normal mammary glands in female Sprague-Dawley rats, an animal model widely used in breast cancer research, across six distinctive developmental stages pre-pubertal, peri-pubertal, pubertal, lactation, and adult parous and age-matched nulliparous.

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Gopalakrishnan K, Teitelbaum SL, Wetmur J, Manservisi F, Falcioni L, Panzacchi S, Gnudi F, Belpoggi F, Chen J