Increased osteoblast viability at alkaline pH in vitro provides a new perspective on bone regeneration

Developing osteoblasts undergo a sequence of three consecutive phases: cell proliferation, extracellular matrix maturation, and mineralization. We investigated pH effects on these phases using the osteoblast-like cell line MC3T3-E1.

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Galow AM, Rebl A, Koczan D, Gimsa J