Polysomal and total RNA in controls and after 10 min global brain ischemia and 8 hours of reperfusion

Complete global brain ischemia (CGBI) and reperfusion occur following resuscitation from cardiac arrest. Different brain neurons are selectively vulnerable to CGBI: pyramidal neurons of hippocampal CA3 survive 10 min CGBI but those of CA1 die at 3 days following 10 min CGBI. CA3 neurons are expected to have more robust stress responses and repair responses than CA1 neurons.

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Wang H, Tri Anggraini F, Chen X, DeGracia DJ