Gene expression in Src-/- RAW264.7 cells infected with VSV and HSV-1

GSE81675

Mus musculus

6 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302)

Submitter Supplied Information

Description

The purpose of this study was to determine what are the effects of Src deficiency on innate antiviral response upon virus infection in RAW264.7 cells. Wild type and Src-/- RAW264.7 cells were infected with vesicular stomatitis virus (VSV) or herpes simplex virus 1 (HSV-1) for 6h. Then the differentially regulated genes were analyzed.

PubMed ID

28049762

Publication Title

The tyrosine kinase Src promotes phosphorylation of the kinase TBK1 to facilitate type I interferon production after viral infection.

Total Samples

Submitter’s Institution

Second Military Medical University

Authors

Li X, Yang M, Yu Z, Tang S, Wang L, Cao X, Chen T

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-81675

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