Robustness of gene expression signatures in leukemia: comparison of three distinct total RNA preparation procedures.

Microarray gene expression (MAGE) signatures allow insights into the transcriptional processes of leukemias and may evolve as a molecular diagnostic test. Introduction of MAGE into clinical practice of leukemia diagnosis will require comprehensive assessment of variation due to the methodologies.

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Campo Dell'Orto M, Zangrando A, Trentin L, Li R, Liu WM, te Kronnie G, Basso G, Kohlmann A