Functional maturation of rat beta cells

The weaning period consist of a critical postnatal window for structural and physiologic maturation of rat beta cells. To investigate transcriptome changes involved in the maturation of beta cells neighboring this period we performed microarray analysis in FACS beta cell enriched populations to detail the global programme of gene expression to identify its changes during this process.

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Larqué C, Velasco M, Barajas-Olmos F, García-Delgado N, Chávez-Maldonado JP, García-Morales J, Orozco L, Hiriart M