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Accession IconGSE76704

Expression data from SHP specific siRNA or nonspecefic siRNA transfected rat astrocytes

Organism Icon Rattus norvegicus
Sample Icon 4 Downloadable Samples
Technology Badge Icon Affymetrix Rat Gene 2.0 ST Array (ragene20st)

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To clarify the effect of SHP in LXRs-mediated signaling pathway, we performed global gene expression analysis of SHP siRNA transfected- or control siRNA transfected- astrocytes after IFN- and LXRs agonist. Microarray analysis revealed that expression of several genes encoding inflammatory mediators were reversed in SHP siRNA transfected-astrocytes, when compared with control siRNA transfected-astrocytes.
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