Comparison of expression data between control, Atg7, Bdh2, Atg7 and Bdh2 dual morphant zebrafish embryos

GSE76508

Danio rerio

10 Downloadable Samples

Affymetrix Zebrafish Genome Array (zebrafish)

Submitter Supplied Information

Description

Bdh2 morphants displayed mitochondrial dysfunction and degradation by autophagy, as well as hypohemoglobinization. Suppression of Atg7 expression in Bdh2 morphants diminished mitochondrial clearance and partly corrected their hemoglobinization defect.

PubMed ID

26929344

Publication Title

Inactivation of 3-hydroxybutyrate dehydrogenase 2 delays zebrafish erythroid maturation by conferring premature mitophagy.

Total Samples

Submitter’s Institution

Case Western Reserve University

Authors

Davuluri G, Song P, Liu Z, Wald D, Sakaguchi TF, Green MR, Devireddy L

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-76508

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