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Accession IconGSE7579

GAR22: A novel target gene of thyroid hormone receptor causes growth inhibition in human erythroid cells

Organism Icon Homo sapiens
Sample Icon 13 Downloadable Samples
Technology Badge Icon Affymetrix Human Genome U95 Version 2 Array (hgu95av2)

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Objective: Thyroid hormone receptors (TRs) are ligand-dependent transcription factors with a major impact on erythroid cell development. Here we investigated TR activity on red cell gene expression and identified TR target genes. The impact of the TR target gene GAR22 (growth arrest specific 2 [GAS2]-related gene on chromosome 22) on red cell differentiation was determined.
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