Gene expression profile of K562 human leukemia cell line after imatinib treatement

GSE75055

Homo sapiens

2 Downloadable Samples

Affymetrix Human Gene 1.0 ST Array (hugene10st)

Submitter Supplied Information

Description

K562 cells when grown with erythropeitin do not respond to Imatinib. Here we are comparing the gene expression profile from imatinib resistant and sensitive cells.

PubMed ID

28319094

Publication Title

Targeting c-FOS and DUSP1 abrogates intrinsic resistance to tyrosine-kinase inhibitor therapy in BCR-ABL-induced leukemia.

Total Samples

Submitter’s Institution

Cincinnati Childrens Hospital and Medical Center

Authors

Kesarwani M, Kincaid Z, Gomaa A, Huber E, Rohrabaugh S, Siddiqui Z, Bouso MF, Latif T, Xu M, Komurov K, Mulloy JC, Cancelas JA, Grimes HL, Azam M

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-75055

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