MALT1 protease activity controls the expression of inflammatory genes in keratinocytes upon Zymosan stimulation

GSE74297

Homo sapiens

3 Downloadable Samples

Affymetrix Human Gene 2.0 ST Array (hugene20st)

Submitter Supplied Information

Description

The protease activity of the paracaspase MALT1 plays an important role in antigen receptor-mediated lymphocyte activation by controlling the activity of the transcription factor NF-kB and is thus essential for the expression of inflammatory target genes.

PubMed ID

26767426

Publication Title

MALT1 Protease Activity Controls the Expression of Inflammatory Genes in Keratinocytes upon Zymosan Stimulation.

Total Samples

Submitter’s Institution

Institute of Medical Genetics Tbingen

Authors

Schmitt A, Grondona P, Maier T, Brändle M, Schönfeld C, Jäger G, Kosnopfel C, Eberle FC, Schittek B, Schulze-Osthoff K, Yazdi AS, Hailfinger S

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-74297

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