Gene expression of MYB wild type and MYB knockdown myeloproliferative K11bL cells

Low levels of MYB promote the development of myeloproliferative neoplasm (MPN). The cell type identified that can transplant the MPN phenotype has been identified as expressing KIT, CD11b and low levels of lineage markers (K11bL).

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Clarke M, Volpe G, Sheriff L, Walton D, Ward C, Wei W, Dumon S, García P, Frampton J