Gene expression profile in the bone marrow of Ptpn6-insufficient mice with neutrophilic dermatosis-like disease (NDLD)

A total number of 1,511 probe sets in the bone marrow showed at least two-fold changes with FDR < 0.05, of which 256 probe sets had over four-fold changes. A group of 63 genes in the bone marrow of NDLD mice had more than a 4-fold change with FDR < 0.0001. From 503 genes encoding proteins with ITIM motif that binds to Ptpn6, 109 were up-regulated and 83 were down-regulated.

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Nesterovitch AB, Arbieva Z, Toth DM, Tharp MD, Glant TT