Kinetic analysis of T cell anergy induction

GSE72731

Mus musculus

14 Downloadable Samples

Affymetrix Murine Genome U74A Array (mgu74a), Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)

Submitter Supplied Information

Description

T cell receptor(TCR) engagement in the absence of costimulation leads to a state of T cell tolerance known as anergy. Anergy induction requires new protein synthesis since it is inhibited by cycloheximide.

PubMed ID

26507712

Publication Title

Ndrg1 is a T-cell clonal anergy factor negatively regulated by CD28 costimulation and interleukin-2.

Total Samples

Submitter’s Institution

Seoul National University College of Medicine

Authors

Oh YM, Park HB, Shin JH, Lee JE, Park HY, Kho DH, Lee JS, Choi H, Okuda T, Kokame K, Miyata T, Kim IH, Lee SH, Schwartz RH, Choi K

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-72731

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