Expression data of bronchoalveolar lavage cells from control or urethane treated AJ mice

GSE7258

Mus musculus

17 Downloadable Samples

Affymetrix Mouse Genome 430 2.0 Array (mouse4302), Affymetrix Murine Genome U74A Version 2 Array (mgu74av2)

Submitter Supplied Information

Description

AJ mouse is susceptible to lung carcinogenesis from urethane treatment and is a good model for human adenocarcinoma. We completed a study using microarray analysis of bronchoalveolar lavage cells from control or urethane treated mice. A unique macrophage expression signature in the lung tumor microenvironment was able to correctly classify the lavage samples.

PubMed ID

18172294

Publication Title

A macrophage gene expression signature defines a field effect in the lung tumor microenvironment.

Total Samples

Submitter’s Institution

UCHSC

Authors

Stearman RS, Dwyer-Nield L, Grady MC, Malkinson AM, Geraci MW

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-7258

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