Develomental Time Course of the Retinal Pigment Epithelial Transcriptome

Purpose: The morphology of the RPE shows minimal change as the neural retina and choriocapillaris differentiate. Nonetheless, initial studies of barrier-related proteins suggest extensive remodeling of the RPE in response to this changing environment. A genomic approach was used to investigate the extent of this remodeling.

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Rizzolo LJ, Chen X, Weitzman M, Sun R, Zhang H