Gene expression in undifferentiated or cyclic adenosine monophosphate-exposed BeWo trophoblast cells

BeWo trophoblast cells differentiate in response to expsure to cyclic adenosine monophosphate (cAMP) analogs. Differentiation includes syncytialization (fusion) and hormonogenesis. The goal of this study was to globally determine transcripts differentially expressed in BeWo trophoblast cells following a 24-h exposure to 250 uM 8-bromo-cAMP.

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Renaud SJ, Chakraborty D, Mason CW, Rumi MA, Vivian JL, Soares MJ