Human induced pluripotent stem cells: diploid, chr7q deletion, spontaneous chr7 correction

GSE65215

Homo sapiens

9 Downloadable Samples

Illumina HumanHT-12 V4.0 expression beadchip

Submitter Supplied Information

Description

Gene expression analysis, a) comparing isogenic karyotypically normal iPSCs to del7q-iPSCs, b) comparing del7q-iPSCs to spontaneously corrected iPSCs. The chr7q deletion results in reduced expression levels of a large number of genes in the chr7q deleted region

PubMed ID

25798938

Publication Title

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells.

Total Samples

Submitter’s Institution

Icahn School of Medicine at Mount Sinai

Authors

Kotini AG, Chang CJ, Boussaad I, Delrow JJ, Dolezal EK, Nagulapally AB, Perna F, Fishbein GA, Klimek VM, Hawkins RD, Huangfu D, Murry CE, Graubert T, Nimer SD, Papapetrou EP

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-65215

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