HP1 has distinct subnuclear localizations, chromatin binding features and functions in embryonic stem cells and differentiating cells [expression]

GSE65121

Mus musculus

12 Downloadable Samples

Affymetrix Mouse Gene 1.0 ST Array (mogene10st)

Submitter Supplied Information

Description

We used microarrays to identify the gene expression changes in Cbx1-/- (HP1beta) knockout embryonic stem cells (ESCs) and Cbx5-/- (HP1alpha) knockout ESCs compared to WT ESCs and in embryoid bodies (EBs) differentiated from those three ESC types.

PubMed ID

26415775

Publication Title

Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells.

Total Samples

Submitter’s Institution

The Hebrew University of Jerusalem

Authors

Mattout A, Aaronson Y, Sailaja BS, Raghu Ram EV, Harikumar A, Mallm JP, Sim KH, Nissim-Rafinia M, Supper E, Singh PB, Sze SK, Gasser SM, Rippe K, Meshorer E

Source Repository

Gene Expression Omnibus (GEO)

Alternate Accession IDs

E-GEOD-65121

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