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GSE64322
Selective Loss of RB in Resistant EGFR Mutant Lung Adenocarcinomas that Transform to SCLC [gene expression]
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Homo sapiens
10 Downloadable Samples
Affymetrix Human Genome U133 Plus 2.0 Array (hgu133plus2)
Submitter Supplied Information
Description
The study was designed to identify the molecular changes that occur in EGFR mutant NSCLCs that become resistant to TKI by transforming to SCLC.
PubMed ID
25758528
Publication Title
RB loss in resistant EGFR mutant lung adenocarcinomas that transform to small-cell lung cancer.
Total Samples
10
Submitter’s Institution
Massachusetts General Hospital
Authors
Niederst MJ
,
Sequist LV
,
Poirier JT
,
Mermel CH
,
Lockerman EL
,
Garcia AR
,
Katayama R
,
Costa C
,
Ross KN
,
Moran T
,
Howe E
,
Fulton LE
,
Mulvey HE
,
Bernardo LA
,
Mohamoud F
,
Miyoshi N
,
VanderLaan PA
,
Costa DB
,
Jänne PA
,
Borger DR
,
Ramaswamy S
,
Shioda T
,
Iafrate AJ
,
Getz G
,
Rudin CM
,
Mino-Kenudson M
,
Engelman JA
Source Repository
Gene Expression Omnibus (GEO)
Alternate Accession IDs
E-GEOD-64322
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